Knilonat 200 mg (Nilotinib)

Knilonat 200 mg (Nilotinib)

Product Name: Knilonat 200 mg
Generic Name: Nilotinib 200 mg

Description:
Knilonat 200 mg contains the active ingredient Nilotinib, a tyrosine kinase inhibitor used primarily in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). It works by blocking certain proteins that promote the growth of cancer cells, helping to slow or stop their spread.

Key Details:
✅ Strength: 200 mg per capsule
✅ Form: Oral capsules
✅ Indication: Used to treat adults with chronic phase and accelerated phase Ph+ CML who are resistant or intolerant to prior therapy (including imatinib).
✅ Mechanism of Action: Selectively inhibits the BCR-ABL tyrosine kinase, preventing cancer cell proliferation.

Usage Instructions:

• Always take as prescribed by your oncologist.

• Typically taken twice daily, approximately 12 hours apart, on an empty stomach (at least 2 hours before or 1 hour after eating).

• Swallow capsules whole with water; do not crush or open.

Common Side Effects:

• Nausea

• Headache

• Fatigue

• Rash

• Muscle pain

• Elevated liver enzymes (detected by blood tests)

Serious Warnings (seek immediate medical attention):

• Irregular heartbeat

• Severe headache or vision changes (possible signs of bleeding or clotting problems)

• Signs of liver problems (yellowing of skin/eyes, dark urine)

Important Notes:

• Regular blood tests are required to monitor response and side effects.

• Avoid grapefruit and grapefruit juice (can increase drug levels).

• Inform your doctor of all medications you are taking to avoid interactions.