Andractim Gel (Dihydrotestosterone 2.5%) Andractim Gel is a prescription-only topical hormone therapy containing 2.5% dihydrotestosterone (DHT), manufactured by Besins Healthcare. It is prescribed by physicians for gynecomastia management, male hypogonadism, and select androgen deficiency conditions. DHT cannot convert to estrogen, which is why clinicians select it specifically when an estrogen-sparing androgen is needed. Regulatory Status Andractim …